diff --git a/crates/api/src/runtime.rs b/crates/api/src/runtime.rs
index 8908483996..4f724875e2 100644
--- a/crates/api/src/runtime.rs
+++ b/crates/api/src/runtime.rs
@@ -267,6 +267,22 @@ impl Config {
         self
     }
 
+    /// Configures whether Cranelift should perform a NaN-canonicalization pass.
+    ///
+    /// When Cranelift is used as a code generation backend this will configure
+    /// it to replace NaNs with a single canonical value. This is useful for users
+    /// requiring entirely deterministic WebAssembly computation.
+    /// This is not required by the WebAssembly spec, so it is not enabled by default.
+    ///
+    /// The default value for this is `false`
+    pub fn cranelift_nan_canonicalization(&mut self, enable: bool) -> &mut Self {
+        let val = if enable { "true" } else { "false" };
+        self.flags
+            .set("enable_nan_canonicalization", val)
+            .expect("should be valid flag");
+        self
+    }
+
     /// Loads cache configuration specified at `path`.
     ///
     /// This method will read the file specified by `path` on the filesystem and
diff --git a/crates/fuzzing/src/generators.rs b/crates/fuzzing/src/generators.rs
index 15715b3a44..d8ab981588 100644
--- a/crates/fuzzing/src/generators.rs
+++ b/crates/fuzzing/src/generators.rs
@@ -66,9 +66,7 @@ pub struct DifferentialConfig {
 impl DifferentialConfig {
     /// Convert this differential fuzzing config into a `wasmtime::Config`.
     pub fn to_wasmtime_config(&self) -> anyhow::Result<wasmtime::Config> {
-        let mut config = wasmtime::Config::new();
-        config.cranelift_debug_verifier(true);
-        config.strategy(match self.strategy {
+        let mut config = crate::fuzz_default_config(match self.strategy {
             DifferentialStrategy::Cranelift => wasmtime::Strategy::Cranelift,
             DifferentialStrategy::Lightbeam => wasmtime::Strategy::Lightbeam,
         })?;
diff --git a/crates/fuzzing/src/lib.rs b/crates/fuzzing/src/lib.rs
index d56295883a..d9f884e616 100644
--- a/crates/fuzzing/src/lib.rs
+++ b/crates/fuzzing/src/lib.rs
@@ -30,3 +30,18 @@ pub(crate) fn init_fuzzing() {
             .expect("should only initialize the rayon thread pool once!");
     })
 }
+
+/// Create default fuzzing config with given strategy
+pub(crate) fn fuzz_default_config(
+    strategy: wasmtime::Strategy,
+) -> anyhow::Result<wasmtime::Config> {
+    init_fuzzing();
+    let mut config = wasmtime::Config::new();
+    config
+        .cranelift_debug_verifier(true)
+        .cranelift_nan_canonicalization(true)
+        .wasm_multi_value(true)
+        .wasm_bulk_memory(true)
+        .strategy(strategy)?;
+    Ok(config)
+}
diff --git a/crates/fuzzing/src/oracles.rs b/crates/fuzzing/src/oracles.rs
index ebee9cc436..f57f13c0eb 100644
--- a/crates/fuzzing/src/oracles.rs
+++ b/crates/fuzzing/src/oracles.rs
@@ -16,18 +16,6 @@ use dummy::dummy_imports;
 use std::sync::atomic::{AtomicUsize, Ordering::SeqCst};
 use wasmtime::*;
 
-fn fuzz_default_config(strategy: Strategy) -> Config {
-    crate::init_fuzzing();
-    let mut config = Config::new();
-    config
-        .cranelift_debug_verifier(true)
-        .wasm_multi_value(true)
-        .wasm_bulk_memory(true)
-        .strategy(strategy)
-        .expect("failed to enable lightbeam");
-    return config;
-}
-
 fn log_wasm(wasm: &[u8]) {
     static CNT: AtomicUsize = AtomicUsize::new(0);
     if !log::log_enabled!(log::Level::Debug) {
@@ -51,7 +39,7 @@ fn log_wasm(wasm: &[u8]) {
 ///
 /// You can control which compiler is used via passing a `Strategy`.
 pub fn instantiate(wasm: &[u8], strategy: Strategy) {
-    instantiate_with_config(wasm, fuzz_default_config(strategy));
+    instantiate_with_config(wasm, crate::fuzz_default_config(strategy).unwrap());
 }
 
 /// Instantiate the Wasm buffer, and implicitly fail if we have an unexpected
@@ -98,7 +86,7 @@ pub fn instantiate_with_config(wasm: &[u8], config: Config) {
 pub fn compile(wasm: &[u8], strategy: Strategy) {
     crate::init_fuzzing();
 
-    let engine = Engine::new(&fuzz_default_config(strategy));
+    let engine = Engine::new(&crate::fuzz_default_config(strategy).unwrap());
     let store = Store::new(&engine);
     log_wasm(wasm);
     let _ = Module::new(&store, wasm);