diff --git a/Cargo.toml b/Cargo.toml
index d78cb4b9f4..22208d23b0 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -14,10 +14,10 @@ default-run = "wasmtime"
 
 [dependencies]
 # Enable all supported architectures by default.
-cranelift-codegen = { version = "0.49", features = ["enable-serde", "all-arch"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
-cranelift-native = "0.49"
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde", "all-arch"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-native = "0.50.0"
 wasmtime = { path = "crates/api" }
 wasmtime-debug = { path = "crates/debug" }
 wasmtime-environ = { path = "crates/environ" }
diff --git a/crates/api/Cargo.toml b/crates/api/Cargo.toml
index f649eccbae..6f39564bb4 100644
--- a/crates/api/Cargo.toml
+++ b/crates/api/Cargo.toml
@@ -13,11 +13,11 @@ name = "wasmtime_api"
 crate-type = ["lib", "staticlib", "cdylib"]
 
 [dependencies]
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-native = "0.49"
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
-cranelift-frontend = "0.49"
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-native = "0.50.0"
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-frontend = "0.50.0"
 wasmtime-runtime = { path = "../runtime" }
 wasmtime-environ = { path = "../environ" }
 wasmtime-jit = { path = "../jit" }
diff --git a/crates/debug/Cargo.toml b/crates/debug/Cargo.toml
index 8ad753c693..1ccaf72be1 100644
--- a/crates/debug/Cargo.toml
+++ b/crates/debug/Cargo.toml
@@ -14,9 +14,9 @@ edition = "2018"
 [dependencies]
 gimli = "0.19.0"
 wasmparser = "0.39.2"
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
 faerie = "0.12.0"
 wasmtime-environ = { path = "../environ", default-features = false }
 target-lexicon = { version = "0.9.0", default-features = false }
diff --git a/crates/environ/Cargo.toml b/crates/environ/Cargo.toml
index 8e6112dcf3..62629ecdf7 100644
--- a/crates/environ/Cargo.toml
+++ b/crates/environ/Cargo.toml
@@ -12,9 +12,9 @@ readme = "README.md"
 edition = "2018"
 
 [dependencies]
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
 lightbeam = { path = "../lightbeam", optional = true }
 indexmap = "1.0.2"
 rayon = "1.2"
@@ -44,7 +44,7 @@ tempfile = "3"
 target-lexicon = { version = "0.9.0", default-features = false }
 pretty_env_logger = "0.3.0"
 rand = { version = "0.7.0", features = ["small_rng"] }
-cranelift-codegen = { version = "0.49", features = ["enable-serde", "all-arch"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde", "all-arch"] }
 filetime = "0.2.7"
 
 [features]
diff --git a/crates/interface-types/Cargo.toml b/crates/interface-types/Cargo.toml
index c7cc8d243c..ffb91aaf5e 100644
--- a/crates/interface-types/Cargo.toml
+++ b/crates/interface-types/Cargo.toml
@@ -12,7 +12,7 @@ edition = "2018"
 
 [dependencies]
 anyhow = "1.0.19"
-cranelift-codegen = { version = "0.49", default-features = false }
+cranelift-codegen = { version = "0.50.0", default-features = false }
 walrus = "0.13"
 wasmparser = { version = "0.39.2", default-features = false }
 wasm-webidl-bindings = "0.6"
diff --git a/crates/jit/Cargo.toml b/crates/jit/Cargo.toml
index 5fec8b6bee..51bb1789ce 100644
--- a/crates/jit/Cargo.toml
+++ b/crates/jit/Cargo.toml
@@ -11,10 +11,10 @@ readme = "README.md"
 edition = "2018"
 
 [dependencies]
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
-cranelift-frontend = "0.49"
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-frontend = "0.50.0"
 wasmtime-environ = { path = "../environ", default-features = false }
 wasmtime-runtime = { path = "../runtime", default-features = false }
 wasmtime-debug = { path = "../debug", default-features = false }
diff --git a/crates/lightbeam/Cargo.toml b/crates/lightbeam/Cargo.toml
index da07aeaf7f..9a118f4afb 100644
--- a/crates/lightbeam/Cargo.toml
+++ b/crates/lightbeam/Cargo.toml
@@ -20,7 +20,7 @@ memoffset = "0.5.1"
 itertools = "0.8"
 capstone = "0.6.0"
 thiserror = "1.0.4"
-cranelift-codegen = "0.49"
+cranelift-codegen = "0.50.0"
 multi_mut = "0.1"
 either = "1.5"
 typemap = "0.3"
diff --git a/crates/misc/py/Cargo.toml b/crates/misc/py/Cargo.toml
index 9acf8ed85b..ee9af74782 100644
--- a/crates/misc/py/Cargo.toml
+++ b/crates/misc/py/Cargo.toml
@@ -15,11 +15,11 @@ name = "_wasmtime"
 crate-type = ["cdylib"]
 
 [dependencies]
-cranelift-codegen = "0.49"
-cranelift-native = "0.49"
-cranelift-entity = "0.49"
-cranelift-wasm = "0.49"
-cranelift-frontend = "0.49"
+cranelift-codegen = "0.50.0"
+cranelift-native = "0.50.0"
+cranelift-entity = "0.50.0"
+cranelift-wasm = "0.50.0"
+cranelift-frontend = "0.50.0"
 wasmtime-environ = { path = "../../environ" }
 wasmtime-interface-types = { path = "../../interface-types" }
 wasmtime-jit = { path = "../../jit" }
diff --git a/crates/misc/rust/Cargo.toml b/crates/misc/rust/Cargo.toml
index 872c8e4e59..2f47219605 100644
--- a/crates/misc/rust/Cargo.toml
+++ b/crates/misc/rust/Cargo.toml
@@ -15,8 +15,8 @@ test = false
 doctest = false
 
 [dependencies]
-cranelift-codegen = "0.49"
-cranelift-native = "0.49"
+cranelift-codegen = "0.50.0"
+cranelift-native = "0.50.0"
 wasmtime-interface-types = { path = "../../interface-types" }
 wasmtime-jit = { path = "../../jit" }
 wasmtime-rust-macro = { path = "./macro" }
diff --git a/crates/obj/Cargo.toml b/crates/obj/Cargo.toml
index 02677e3857..0f4b6d36e2 100644
--- a/crates/obj/Cargo.toml
+++ b/crates/obj/Cargo.toml
@@ -11,9 +11,9 @@ readme = "README.md"
 edition = "2018"
 
 [dependencies]
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
 wasmtime-environ = { path = "../environ" }
 faerie = "0.12.0"
 more-asserts = "0.2.1"
diff --git a/crates/runtime/Cargo.toml b/crates/runtime/Cargo.toml
index 30cbf421a8..f255c7c3ef 100644
--- a/crates/runtime/Cargo.toml
+++ b/crates/runtime/Cargo.toml
@@ -11,9 +11,9 @@ readme = "README.md"
 edition = "2018"
 
 [dependencies]
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
 wasmtime-environ = { path = "../environ", default-features = false }
 region = "2.0.0"
 lazy_static = "1.2.0"
diff --git a/crates/wasi-c/Cargo.toml b/crates/wasi-c/Cargo.toml
index dafba67b58..477880a03d 100644
--- a/crates/wasi-c/Cargo.toml
+++ b/crates/wasi-c/Cargo.toml
@@ -14,9 +14,9 @@ edition = "2018"
 wasmtime-runtime = { path = "../runtime" }
 wasmtime-environ = { path = "../environ" }
 wasmtime-jit = { path = "../jit" }
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
 target-lexicon = "0.9.0"
 log = { version = "0.4.8", default-features = false }
 libc = "0.2.60"
diff --git a/crates/wasi-common/Cargo.toml b/crates/wasi-common/Cargo.toml
index 26d4751b45..6e6af87bf5 100644
--- a/crates/wasi-common/Cargo.toml
+++ b/crates/wasi-common/Cargo.toml
@@ -42,7 +42,7 @@ wasmtime-environ = { path = "../environ" }
 wasmtime-jit = { path = "../jit" }
 wasmtime-wasi = { path = "../wasi" }
 wasmtime = { path = "../api" }
-cranelift-codegen = "0.49.0"
+cranelift-codegen = "0.50.0"
 target-lexicon = "0.9.0"
 pretty_env_logger = "0.3.0"
 tempfile = "3.1.0"
diff --git a/crates/wasi/Cargo.toml b/crates/wasi/Cargo.toml
index 0b4ff60a87..7d0c898459 100644
--- a/crates/wasi/Cargo.toml
+++ b/crates/wasi/Cargo.toml
@@ -15,9 +15,9 @@ wasmtime-runtime = { path = "../runtime" }
 wasmtime-environ = { path = "../environ" }
 wasmtime-jit = { path = "../jit" }
 wasi-common = { path = "../wasi-common" }
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
 target-lexicon = "0.9.0"
 log = { version = "0.4.8", default-features = false }
 
diff --git a/crates/wast/Cargo.toml b/crates/wast/Cargo.toml
index 356e9b36d8..85d42e80ac 100644
--- a/crates/wast/Cargo.toml
+++ b/crates/wast/Cargo.toml
@@ -11,9 +11,9 @@ readme = "README.md"
 edition = "2018"
 
 [dependencies]
-cranelift-codegen = { version = "0.49", features = ["enable-serde"] }
-cranelift-entity = { version = "0.49", features = ["enable-serde"] }
-cranelift-wasm = { version = "0.49", features = ["enable-serde"] }
+cranelift-codegen = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-entity = { version = "0.50.0", features = ["enable-serde"] }
+cranelift-wasm = { version = "0.50.0", features = ["enable-serde"] }
 wasmtime-jit = { path = "../jit" }
 wasmtime-runtime = { path = "../runtime" }
 wasmtime-environ = { path = "../environ" }